Metasemantics focuses on mapping the conceptual space within which semantic theories are constructed; in particular, metasemantics focuses on analyzing and relating concepts like reference, truth, utterances, anaphora, definition, etc...https://msu.edu/~orourk51/431-Phil/2015-Fall/Handouts/Philosophical/431F15-SemsMetasems.pdf
An important consideration is the degree to which semantic consideration should be empirical as opposed to conceptual. It is worth noting that any scientist, no matter how applied, can bump up against conceptual questions. In this case, it would appear that there is reason to expect work for both the philosopher and the scientist. (Compare and constrast this with the project of accounting for any other human system.)
The conceptual side of metasemantics resolves into metaphysical considerations and epistemic considerations.
We must also be sensitive to results produced along the empirical dimension, in linguistics, psychology, and neuroscience. This includes results from the following two sources of semantically relevant data ... 1. Facts about how natural languages are actually used by members of the relevant speech communities. 2. The semantic intuitions of those who speak the languages.
The Metasemantic Strategy: Lay bare the central semantic concepts and their interrelations, creating a conceptual framework for understanding semantic phenomena. – Grice, e.g.